Germicide and method of producing same



Patented July 25, 1944 I v 2,354,334 onmvncma AND MElHOD or PRODUCING Anthony J. Salle, West Los Angeles, as Howard L. Guest, Ocean Park, hall to Leo A. Gunther, Robbins, Calif.

No Drawing. Application October 27, 1942, Serial No. 463,543

7 Claims. (Cl. 167-31) This invention relates to g'ermicides of the phenol group that are in oxidized form, such as chlorophenol and sulfophenol.

The object of the invention is to greatly increase the germicidal properties of chlorophenol, sulfophenol, or-any of the solutions of phenol generally in which the phenol is in the oxidized form, thus tion, one gram molecular weight of a reducing agent, such as ferrous chloride, ferrous sulphate, manganous chloride or manganous sulphate.

By the above addition of the reducing agent, the killing power of the solution as applied to micro-organisms, such as Staphylococcus aureus, is substantially increased so that the per cent concentration of the resultant solution may be from one-third to one-half of the concentration required, before the addition, for accomplishing the same results.

By thi addition, the objectionable causticity to tissue of the phenol is correspondingly reduced and the resultant product is less caustic to tissue.

It is pertinent to note that in a conventional solution of chlorophenol, without the addition of a reducing agent, the concentration is such that it is caustic to tissue if it has the requisite killing power to be effective as a germicide, as demonstrated by the following; the least lethal dilution of chlorophenol is 1:500; the effective dilution is -l:100. The least lethal dilution of improved chlorophenol is 1:1400; the effective dilution is 1:460.

The advantages of the invention are therefore,

., assignors of one- 2. The method of increasing the germicidal properties of phenols that are in oxidized form that comprises adding to each gram. molecular weight of the phenol one gram molecular weight of a reducing agent from the group; ferrous chloride, ferrous sulfate, "manganous chloride, manganous sulfate.

3. The method of increasing the germicidal property of one of the group; chlorophenol, sulfophenol, that comprises adding to each gram molecular weight thereof one gram molecular weight of one ofthe group; ferrous chloride, ferrous sulfate, manganous chloride, manganous sulfate.

4. A germicidal product comprising one of the phenols that is in oxidized form and areducing agent from one of the group; ferrous chloride, ferrous sulfate, manganous chloride, manganous sulfate, in the proportion of one gram molecular weight of the phenol to one gram molecular weight of the reducing agent.

5. A germicidal product comprising one of the phenol in the group; chlorophenol, sulfophenol, and a reducing agent from one of the group; ferrous chloride, ferrous sulfate, manganous chloride, manganous sulfate, in the proportion of one gram molecular weight of the reducing agent to. each gram molecular weight of the phenol.

6. A germicidal solution comprising one of the phenols in the group; chlorophenol, sulfophenol and a reducing agent from one of the group; ferrous chloride, ferrous sulfate, manganous chloride, manganous sulfate, in the proportion of onev gram molecular weight of the reducing agent to each gram molecular weight of the phenol.

7. A germicidal solution having substantially the same killing power to Staphylococcus aureus -of a 1:100 solution of chlorophenol that comprises substantially a 1:1400 solution of chlorophenol and a reducing agent from one of the group; ferrous chloride, ferrous sulphate, manganous chloride, manganous sulfate, in the proportion of one gram molecular weight of the reducing agent to each-gram molecular weight of .45 the chlorophnol.

ANTHONY J. SALLE. HOWARD L. GUEST. 

